Composed of an avirulent live culture of Bordetella bronchiseptica bacteria and modified live canine parainfluenza virus. Now with adenovirus type 2(and hepatitis). Give 0.5 ml into each nostril. Revaccinate annually. Requires mixing. Do not inject; for intranasal use only All vaccines are shipped overnight. A $34.95 flat rate fee is charged for all orders containing vaccines. Someone should be present to sign for and receive the vaccine order when it ships to you. For more shipping info click here.